Office of Institutional Advancement

AASLD: The Liver Meeting

Group

Presenter:
Jonathan Fenkel, MD

Presentation topics

  1. Presenting a poster on behalf of a multidisciplinary group from Jefferson, Penn, and Drexel on “Pulse Shaping for Improved Diagnosis of Portal Hypertension Using Subharmonic Aided Pressure Estimation” in a group including Flemming Forsberg, Susan Shamimi-Noori, and Colette Shaw, Jaydev Dave and John Eisenbrey in radiology.
  2. Coauthor for Dr. Bolin Niu’s poster, “Obstetricians’ Knowledge and practices regarding chronic hepatitis B in pregnancy.”
This is a collaborative effort led by Dr. Forsberg in Jefferson’s Department of Radiology between Jefferson, Penn and Drexel. We hope one day we will be able to estimate the liver’s portal pressures non-invasively and replace the current invasive pressure measurements obtained via transjugular approach. Our group has researched the potential for external ultrasoundbased subharmonic imaging aided by a bubble contrast agent. We are hopeful this technology will eventually make patient care safer by eliminating the need for invasive, direct pressure measurements.

Presenter:
Dina Halegoua-De Marzio, MD

Presentation topics

  1. Kushner T, Shaw PA, Kalra A, Magaldi L, Monpara P, Bedi G, Krok K, Centkowski S, Dalldorf K, D’souza J, Halegoua-De Marzio D, Goldberg D, Levine L, Srinivas SK, Lewis JD, Forde K, Lo Re V III. Incidence, Determinants, and Outcomes of Pregnancy-Associated Hepatitis B Flares: A Regional Hospital-Based Cohort Study. AASLD Liver Meeting in Boston, MA, November 2016.
  2. Nui B, Halegoua-De Marzio D, Fenkel JM, Herrine SK. Obstetricians’ Knowledge and Practices Regarding Chronic Hepatitis B in Pregnancy. AASLD Liver Meeting in Boston, MA, November 2016.
  3. Halegoua-De Marzio D (role- Program Chair), Chang, M. Program Director’s Workshop. AASLD Liver Meeting, Boston MA, November 13, 2016.
There are 2.2 million people with chronic hepatitis B (HBV) infection in the United States. Despite the availability of a vaccine and hepatitis B immune globulin, HBV vertical transmission may still occur. In pregnant women with high viral loads, third trimester initiation of antiviral agents can reduce the risk of vertical transmission further. This study set out to assess OBGYN knowledge and clinical practice when treating pregnant women with chronic HBV. OBGYNs self report that they screen almost all pregnant patients for chronic HBV at the first prenatal visit. However, significant gaps exist in resident comfort and education in the management of pregnant patients with HBV, though improvement is seen through years of training.

Presenter:
Steven K. Herrine, MD

Presentation topics

  1. Niu B, Halegoua-DeMarzio D, Fenkel JM, Herrine SK. Obstetricians’ knowledge and practices regarding chronic hepatitis B in pregnancy. Hepatology 2016;64:848A. Poster presentation to American Association for the Study of Liver Diseases Annual Meeting 2016, Boston, MA, November 13, 2016.
  2. Reddy S, Reddy KG, Herrine SK, Koteish AA, Sterling RK, Russo MW, McDonald FS, Fix OK. A competency-based medical education pilot for training and certification in gastroenterology and transplant hepatology. Hepatology 2016;64:895A. Poster presentation to American Association for the Study of Liver Diseases Annual Meeting 2016, Boston, MA, November 13, 2016.
Training physicians has become more complex with increasing technology. There is a need to increase medical delivery systems and maintain patient-centered compassionate approaches to care. The American Association for the Study of Liver Diseases, the leading organization devoted to the care of patients with liver disease, teamed up with the American Board of Internal Medicine to institute a training paradigm using competence as the measure of success. This research outlines the training pilot program.

Presenter:
Jesse Civan, MD

Presentation topic: Intrahepatic Cholangiocarcinoma

  1. Raja Koteswar Dhanekula, Donald G. Mitchell, John L. Farber, Ashwin Sama, Jesse Civan. Intrahepatic Cholangiocarcinoma Presenting as LI-RADS 5 “HCC.”
Hepatocellular carcinoma is a particular form of liver cancer. This is an unusual cancer in the sense that a biopsy is usually unnecessary in making the diagnosis because the appearance of the cancer is so prevalent on an MRI. This research demonstrates that another form of cancer, cholangiocarcinoma, can mimic the appearance of hepatocellular carcinoma on an MRI, to an extent which may not previously have been appreciated, thus making diagnosis for cholangiocarcinoma easier for physicians.