Congenital heart disease is among the most prevalent forms of human birth defects. Our lab seeks to understand the mechanisms regulating the development of the cardiovascular system and the processes that go awry in congenital heart disease. We are using genetics, cell biology and 3-dimensional imaging to uncover signaling pathways mediating intercellular communications between distinct populations of progenitors regulating morphogenesis of the heart and associated blood vessels.
1020 Locust Street
Philadelphia, PA 19107