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Lucia Languino, PhD

Contact Dr. Languino

Sidney Kimmel Cancer Center
233 S. Tenth Street, Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. Unique pattern of neutrophil migration and function during tumor progression
  2. Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer
  3. Syntaphilin ubiquitination regulates mitochondrial dynamics and tumor cell movements
  4. Evaluation of Drug Combination Effect Using a Bliss Independence Dose–Response Surface Model
  5. Prostate cancer sheds the αvβ3 integrin in vivo through exosomes
  6. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
  7. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer
  8. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes
  9. A neuronal network of mitochondrial dynamics regulates metastasis
  10. Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development
  11. v-Src oncogene induces Trop2 proteolytic activation via cyclin D1
  12. Exosome-mediated transfer of αvβ3 integrin from tumorigenic to nontumorigenic cells promotes a migratory phenotype
  13. αvβ6 integrin promotes castrate-resistant prostate cancer through JNK1-mediated activation of androgen receptor
  14. Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
  15. β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation
  16. The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
  17. CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation
  18. Exosome-mediated transfer from the tumor microenvironment increases TGFβ signaling in squamous cell carcinoma
  19. A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice
  20. Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism