David Rosen, MD

Contact Dr. Rosen

925 Chestnut Street
6th floor
Philadelphia, PA 19107

(215) 955-6760
(215) 503-3736 fax

Most Recent Peer-reviewed Publications

  1. A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursors
  2. MEPE has the properties of an osteoblastic phosphatonin and minhibin
  3. Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: A double-blind, placebo-controlled pilot study
  4. The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: Evidence for in vivo biological activity
  5. Studies in cranial suture biology: Part I. Increased immunoreactivity for TGF-β isoforms (β1, β2, and β3) during rat cranial suture fusion
  6. Treatment of ovariectomized rats with the complex of rhIGF-I/IGFBP-3 Increases cortical and cancellous bone mass and improves structure in the femoral neck
  7. The effect of systemically administered rhIGF-I/IGFBP-3 complex on cortical bone strength and structure in ovariectomized rats
  8. Systemic administration of rhIGF-I or rhIGF-I/IGFBP-3 increases cortical bone and lean body mass in ovariectomized rats
  9. Benefit of systemically administered rhIGF‐I and rhIGF‐I/IGFBP‐3 on cancellous bone in ovariectomized rats
  10. Systemic administration of recombinant transforming growth factor beta 2 (rTGF-β2) stimulates parameters of cancellous bone formation in juvenile and adult rats
  11. Osteoblastic gene expression during adipogenesis in hematopoietic supporting murine bone marrow stromal cells
  12. Bone morphogenetic proteins (BMP-2 and BMP-3) induce the late phase expression of the proto-oncogene c-fos in murine osteoblastic MC3T3-E1 cells
  13. Bovine bone activin enhances bone morphogenetic protein-induced ectopic bone formation
  14. Bone-inducing implants in head and neck surgery: An experimental study
  15. Transforming Growth Factor-β2 Enhances the Osteoinductive Activity of a Bovine Bone-Derived Fraction Containing Bone Morphogenetic Protein-2 and 3
  16. Bone morphogenetic proteins (BMP‐2 and BMP‐3) promote growth and expression of the differentiated phenotype of rabbit chondrocytes and osteoblastic MC3T3‐E1 cells in vitro
  17. Amino acid sequence of bovine osteoinductive factor
  18. Matrix proteins of the skeleton
  19. Osteoinductive factor (OIF) and transforming growth factor-beta (TGFβ) differentially modulate the expression of osteoblastic markers by bone marrow stromal cells
  20. Osteoinductive factor inhibits formation of human osteoclast-like cells