Philadelphia University + Thomas Jefferson University
Sidney Kimmel Medical College
Department of Dermatology & Cutaneous Biology

Macarak, Edward

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Edward Macarak, PhD

Edward Macarak, PhD

Contact Dr. Macarak

Bluemle Life Sciences Building, Room 424
233 South Tenth Street
Philadelphia, PA 19107

(215) 503-5775


Most Recent Peer-Reviewed Publications

  1. Trametinib prevents mesothelial-mesenchymal transition and ameliorates abdominal adhesion formation
  2. Human fibrotic diseases: Current challenges in fibrosis research
  3. Pathobiological mechanisms of peritoneal adhesions: The mesenchymal transition of rat peritoneal mesothelial cells induced by TGF-β1 and IL-6 requires activation of Erk1/2 and Smad2 linker region phosphorylation
  4. New frontiers in fibrotic disease therapies: The focus of the Joan and Joel Rosenbloom Center for Fibrotic Diseases at Thomas Jefferson University
  5. Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment
  6. Keloid pathogenesis: Potential role of cellular fibronectin with the EDA domain
  7. Absence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle
  8. Mechanosensitive release of adenosine 5′-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A mechanism for purinergic involvement in chronic strain
  9. Recombinant insulin-like growth factor-1 activates satellite cells in the mouse urethral rhabdosphincter
  10. Urinary diversion results in marked decreases in proliferation and apoptosis in fetal bladder
  11. Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X 7 receptors
  12. Mechanical properties of the fetal bovine bladder lamina propria and their correlation with changes in extracellular matrix
  13. Effect of fibroblast growth factor-1 on the expression of early growth response-1 in human periodontal ligament cells
  14. β and γ-Sarcoglycans are Decreased in the Detrusor Smooth Muscle Cells of the Partially Obstructed Rabbit Bladder
  15. Altered Extracellular Matrix Expression in the Diverted Fetal Sheep Bladder
  16. Smooth muscle trans-membrane sarcoglycan complex in partial bladder outlet obstruction
  17. Molecular response of the bladder to obstruction
  18. Compression and tension: Differential effects on matrix accumulation by periodontal ligaments fibroblasts in vitro
  19. Partial bladder outlet obstruction alters Ca2+ sensitivity of force, but not of MLC phosphorylation, in bladder smooth muscle
  20. Regulation of Cyr61/CCN1 gene expression through RhoA GTPase and p38MAPK signaling pathways: Role of CREB and AP-1 transcription factors