Office of Institutional Advancement

Jefferson Physician & Fellow ACG Presentations

Jefferson Physician and Fellow ACG Presentations

1. David Kastenberg–Patient Predictors For Inadequate Bowel Preparation In Colonoscopy: A Meta-Analysis

Our goal is to minimize patients’ risk for inadequate preparation. This will increase the effectiveness of colonoscopy by detecting more pre-cancerous polyps, substantially lowering the chance of getting colon cancer after colonoscopy “interval cancer,” and reducing the chance they will have to repeat the colonoscopy before they would ordinarily have been due – saving days lost from work/avoiding co-pays for medications and the procedure/etc.

2. Andrew Kistler, Daniel M. Quirk–Inpatient Management of Gastrointestinal Bleeding in Patient Receiving Target Specific Oral Anticoagulants

There is limited data on patients taking oral anticoagulants that experience gastrointestinal bleeding. This study may help develop new protocols on how to manage these patients both medically and endoscopically.

3. David Kastenberg–Multi-Center Prep Study

CEE offers a non-invasive method to visualize the colon that doesn’t require sedation and can potentially be done at home and on the patient’s schedule. Research suggests it works as well as CT colonography. At Jefferson, we are participating in a national study comparing CTC and CEE for screening in subjects average risk for CRC. While the technology is very exciting, the area most challenging is the preparation regimen.

4. Christina Tofani/Anthony Infantalino–Barrett’s Esophagus Successfully Eradicated with Polypectomies and Radiofrequency Ablation

Polypoid dysplasia in Barrett’s is quite rare, with very few cases in literature. However, they appear to share similar clinicopathologic and molecular features as typical dysplasia seen in Barrett’s. In the literature, all cases of polypoid were treated with esophagectomy when adenocarcinoma or high-grade dysplasia were identified. We presented two cases of polypoid Barrett’s. In the first case, the patient had eradication of low-and high-grade dysplastic tissue after treatment with RFA. However, case two had progression of disease to invasive carcinoma in the setting of one RFA treatment and esophagectomy was recommended.

Polypoid Barrett’s is uncommon and challenging to manage. Hopefully, our two cases will bring this rare entity to light to improve the care of patients presenting with Barrett’s in this form.