The Raphael Center for Neurorestoration blends technological advances with clinical and surgical breakthroughs to restore, promote, maintain, and improve function in individuals affected by debilitating neurological disorders. Housed within the Vickie and Jack Farber Institute for Neuroscience, this center is an ecosystem of discovery and a powerful catalyst for innovation, rapidly translating promising ideas and concepts into life-changing interventions for mobility issues, cognitive dysfunction, and chronic pain.
Jefferson’s neurorestoration team is forging bold new ground at the intersection of technological, rehabilitative, and neurological innovation—and philanthropy has been the catalyst propelling us forward.
The Cortimo™ Trial
The Cortimo™ clinical trial was a milestone in neurorestoration and a successful proof of principle for the vision of the Raphael Center for Neurorestoration.
With the aim to develop a comprehensive brain-computer interface (BCI) system to restore impaired arm control and functionality for a stroke patient, the trial utilized brain-derived signals to control a robotic device that fit over the patient’s weaker arm.
Leading the Way
The success of the Raphael Center for Neurorestoration is built on our high-impact advances in the neurorestoration field, a sampling of which can be found below.
Mijail Serruya, MD, PhD
Assistant Professor, Department of Neurology
Since joining Jefferson in 2011, Dr. Serruya has played a pivotal role in the Department of Neurology, lending his expertise in brain-computer interfaces (BCIs) to form the Raphael Center for Neurorestoration. As a neurologist and a neuroscientist, he works with implantable devices to restore and augment independent function in children and adults with neurological disease or injury. With skills in neurophysiology, holistic integrative medicine, and clinical research, Dr. Serruya’s multidisciplinary approach leverages Jefferson’s robust research infrastructure, academic programs, and industry partnerships to conduct high-impact clinical and translational research in neurorestoration.
Alessandro Napoli, PhD
Research Lead Engineer
As a biomedical engineer, Dr. Napoli’s areas of expertise are physiological signal processing, brain computer interfaces, and the application of engineering tools to address clinical needs. He earned his PhD in Engineering from Temple University in May 2014, and has led numerous research projects on the functional and neural applications of BCIs. As the research lead in Jefferson’s Raphael Center for Neurorestoration, he is working to expand the capabilities of an existing elbow/wrist/hand orthosis device (MyoPro, Myomo, MA) to be able to use brain-derived signals to help stroke patients restore control of an impaired arm. He is responsible for designing the Raphael Center for Neurorestoration’s BCI system from the ground up, developing a revolutionary tool for the future of neurorestorative care.
Our vision is to boldly go where no academic medical center has gone before. Your partnership can provide the “warp drive” to get us there. In the timeless words of Jean-Luc Picard, “Things are only impossible until they are not.” Let’s make the impossible possible, together.